I am not sure which module you are using, but I bought one of the 'helicopter type' modules, and opened it up just to check the signals anyway. A lot of RC people use these so the pinouts online were correct anyway.
I opened it up again an hour ago, and like you found, the VDD pin appears to be tied to Gnd. Interestingly the USB data pins appear to go to an unused 8 pin chip location. I am not sure what that is meant for, but possibly an alternate connector if the same module was used for USB, although unless VDD is tied to GND through an optional resistor, that wouldn't make sense either.
The datasheets and everything else suggest that there is no restriction on using USB and serial at the same time. U-centre allows you to enable and disable different things for the different interfaces. It appears that you can even send different messages to different interfaces.
I believe that you can't use SPI and the UART at the same time though, given that they use the same pins

I2C/DDC pins are available though and again you should be able to use that at the same time.