The few times I have got over 46 knot peaks are all quite different.
eg:
Sept 27, 2009. 45-60 knots. A little bit of footage from it in the Quickly Go Mad video.
Extreme survival conditions for me. CA40, KA 20 assy fin, 2009 Koncept rigged with more downhaul and outhaul than I ever imagined I would use. For most of the run I was thinking I was going to get swatted any second. When I finally got broad enough that I could sort of hang onto the power, the chop/corrugations was extreme and the board was hammering so hard it was jarring my vision. I just ran out of bottle and backed off while I was still accelerating.

The next time on September 16th 2010 was much milder. I was on the 2009 5m Koncept with the same board and fin with 4-5kg of lead in my vest. The wind was WSW and around 30-35 with some nice, not too violent squalls, probably 35-40 knots. I was lucky enough to latch onto one of those just after a bit of a lull so the water was still fairly flat and it came on just as I got to the best angle on the course. It felt fast but nowhere near as violent as the other one and I actually felt quite comfortable. I was actually a bit surprised to see the speed. I stopped right next to Sam Parker who had also just done his fastest run and had a peak almost identical so I knew the display was right.
Both sails were rigged on RDM masts (the only option for the 4.4m) and they work just great on them, but this is very sail brand and design specific.
The common factor in almost all of my best runs is the conditions. A good gust of wind at just the right angle at just the right part of the run with the right angle where I was set up and ready for it and could manage the maximum power.
Too broad and you don't have the power, too tight and you can't use the power. Too much wind for the sail size and you can't get into the course to get the right angle without crashing out, and if you can survive that it can be waaaay too choppy to survive the high speed part. I am convinced that the best speeds for me come in less extreme winds. 35-40 knots is plenty! But everything else has to come together as well. Even the tide state can drastically effect the water state on the course.
Summing up:
-A great combination of gear that you are familiar with and is well tuned so you have full confidence in it.
-Water as flat as possible (it will never be really flat in 45+ knots conditions unless you are on Lake George

)
- 30-40 knots of wind at just the right angle.
OK, Lake George is an exception:
-The water is very flat there no matter how deep you go or how far you go down wind (as long as you are over the weed).
-The SE high pressure thermal wind is very steady so you can't rely on a big gust for a big peak.
-It is actually quite easy to go too deep off the wind at LG!
-You need to have as much sail as you can handle efficiently because you aint gunna get a lucky gust.

-You really, really do need a weed speed fin!

-I am really disappointed that I missed the big day in February!

Oh, one more speed tip: use an adjustable outhaul and when you get off the wind, let it all go to the point the sail is touching the boom. (Not applicable in 45-60 knots!

)
Disclaimer: This is what seems to work for me. Your milage might vary....